Microbiological, serological, and histopathological features of experimental Chlamydia trachomatis urethritis in chimpanzees.
نویسندگان
چکیده
A laboratory-passaged genital strain of Chlamydia trachomatis and two unpassaged genital strains from patients with nongonococcal urethritis were inoculated intraurethrally into three young male chimpanzees. Chlamydia were recovered from the urethra of two animals and specific antibody responses were detected in all of them. Furthermore, a urethral polymorphonuclear leucocyte response, but not an overt discharge, occurred in all the chimpanzees about 1-2 weeks after inoculation. None of these events occurred in a chimpanzee inoculated with medium only. At necropsy three months after inoculation the submucosa of the urethra of one chimpanzee was densely infiltrated with small round cells. This suggests that a similar chronic lymphocytic response may occur in human chlamydial infection of the urethra.
منابع مشابه
Microbiological and serological study of non-gonococcal urethritis with special reference to Mycoplasma genitalium.
Twenty-two men with non-gonococcal urethritis (NGU), 19 with gonorrhoea, and 22 without urethritis were examined for various micro-organisms. Chlamydia trachomatis was isolated from the urethra of 45% of men with NGU, 21% of those with gonorrhoea, but from none without urethritis. Ureaplasma urealyticum but not Mycoplasma hominis was recovered from a larger proportion of men with NGU than from ...
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Current problems of perinatal Chlamydia trachomatis infections
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ورودعنوان ژورنال:
- The British journal of venereal diseases
دوره 57 1 شماره
صفحات -
تاریخ انتشار 1981